research article Clinical outcomes for Andersson Lesion in Patints with Ankylosing Spondylitis By Transforaminal Thoracolumbar Intervertebral Fusion Surgery
Authors: Zheng Huang1-3, Ji Guo1-3, Jianpo Zhang1-3, Licheng Wei1-3, Jiqing Wang1-3, Yongwei Jia1-3*
*Corresponding Author: Yongwei Jia, Department of Spine Surgery, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No.540 Xinhua Road, Shanghai 200052, PR China
1Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
2Shanghai Guanghua Hospital of Integrative Medicine, Shanghai, China
3Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China
Received Date: 22 April, 2022
Accepted Date: 03 May, 2022
Published Date: 06 May, 2022
Citation: Huang Z, Guo J, Zhang J, Wei L, Wang J, et al. (2022) Clinical outcomes for Andersson Lesion in Patints with Ankylosing Spondylitis By Transforaminal Thoracolumbar Intervertebral Fusion Surgery. J Orthop Res Ther 7: 1227 DOI: https://doi.org/10.29011/2575-8241.001227
Abstract
Bcacground：Andersson Lesion (AL) is a rare complication of ankylosing spondylitis and its clinical outcome of surgical treatment needs more exploration.
Objective: To assess safety and efficacy of Transforaminal Thoracolumbar Intervertebral Fusion (TTIF) in the treatment of ankylosing spondylitis(AS) patients with thoracolumbar AL.
Methods: 14 patients with thoracolumbar AL who suffered from back pain, spinal instability or kyphotic deformity were retrospectively recruited. The clinical outcomes were evaluated with Visual Analog Scale (VAS) and Oswestry Disability Index (ODI). Radiological outcomes were measured with Local Kyphotic (LK) angle and General Kyphotic (GK) angle.
Results: The VAS score was improved to 2.4 ± 0.5 from 8.0±0.2 (p<0.01), and ODI score was decreased from 64.0 ±6.9 to 17.0 ±3.7 (p<0.01). One patient with neurological deficit showed an improvement in the Frankel grade from C to D and all others were grated E-level before and after surgery. For radiological outcomes, patients’ LK angel was reduced from 18.5 ± 7.2 to 11.0 ± 6.4 (p<0.01) and GK angel was reduced to 38.6 ±8.8 from 42.8 ±10.4 (p<0.01) at the 1-year follow-up.
Conclusion: For AS patients with thoracolumbar AL, TTIF is safe and effective, which can achieve good fusion and satisfactory radiological and clinical outcomes.
Keywords: Andersson Lesion; Ankylosing Spondylitis; Kyphosis; Transforaminal Thoracolumbar Intervertebral Fusion
Abbreviations: TTIF: Transforaminal Thoracolumbar Intervertebral Fusion; AS: Ankylosing Spondylitis; AL: Andersson Lesions; VAS: Visual Analogue Scale; ODI: Oswestry Disability Index; LK: Local Kyphotic; GK: General Kyphotic; CT: Computed Tomography; MRI: Magnetic Resonance Imaging; BMD: Bone Mineral Density; DEXA: Dual-Energy X-Ray Absorptiometry; SPO: Smith-Peterson Ostomy; SD: Standard Deviation