Case Report Marijuana Induced Coronary Vasospasm – Case Report
by Mohammad Haydar1,2*, Elliott Cohen1, George Habib1, Uriel Levinger1,2
1Internal Department C , Laniado Medical Center , Netanya, Israel
2Adelson School of Medicine at Ariel University, Israel
*Corresponding author: Mohammad haydar,Specialist physician, Laniado Netanya Medical Center, Internal Medicine Department, Israel
Received Date: 8 November, 2023
Accepted Date: 14 November, 2023
Published Date: 0 November, 2023
Citation: Haydar M, Cohen E , Habib G , Levinger U. (2023). Marijuana Induced Coronary Vasospasm – Case Report. Cardiol Res Cardiovasc Med 8:212.https://doi.org/10.29011/2575-7083.100212
Keywords: Chest Pain, Cardiology, Angina, Myocardial Infarction, Cardiac Catheterization
Coronary vasospasm is a well-known condition causing acute chest syndrome and can lead to myocardial infarction, ventricular arrhythmias, and even sudden cardiac death. While there are extensive case series showing the association of coronary vasospasm with drugs like cocaine [1], the association of marijuana with coronary vasospasm has not been reported frequently.
Smoking of marijuana has been reported as a trigger of coronary artery disease and especially acute myocardial infarction (MI). The risk of onset of MI is elevated 4.8 times in the first hour after marijuana use and rapidly decreases thereafter; which may be explained by marijuana induced coronary vasospasm [1]. The effects of the active ingredients in marijuana have been well studied and reported substantially in the literature. When smoked, marijuana results in a rapid, dose-dependent tachycardia by 20-100%, an increase in blood pressure, and an increase in cardiac output by > 30%. This in turn leads to increased oxygen demand, which is augmented by the vasoconstriction endothelial damage by smoking and activation of CB1 receptors by marijuana [2].