Mediastinal Cystic Teratoma Masquerading as Recurrent Pneumonia
Muhammad Sajawal Ali1, Benjamin I2, Divyanshu Mohananey3, Ahya Awais4, Akshay Kohli5
1Division of Pulmonary, Critical Care and Sleep Medicine, Medical College of Wisconsin, Milwaukee, USA
2Department of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA
3Department of Hospital Medicine, Cleveland Clinic, Cleveland, Ohio, USA
4Lahore Medical and Dental College, Lahore, Pakistan
5Maulana Azad Medical College, New Delhi, India
*Corresponding author: Muhammad Sajawal Ali, Division of Pulmonary, Critical Care and Sleep Medicine, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, Wisconsin 53226, Milwaukee, USA, Tel: +414 955-7040; Fax: +414 955-6211 E-mail: : muali@mcw.edu
Received Date: 29 November, 2016; Accepted Date: 30 November, 2016; Published Date: 01 November, 2016
Citation: Ali MS, Benjamin I, Mohananey D, Awais A, Kohli A (2016) Mediastinal Cystic Teratoma Masquerading as Recurrent Pneumonia. Ann Case Rep 2016: J128. DOI: 10.29011/2574-7754/100028
A 37-year-old lady presented with 4 days of fever, chills and productive cough. Over the last one year, she had on multiple instances been diagnosed with right middle lobe (RML) pneumoniaand treated with antibiotics, each time with incomplete resolution of symptoms. Chest X-ray on admission revealed a RML dense opacity with an air fluid level (Figure 1, arrow), concerning for a lung abscess or a necrotic tumor. However, CT chest revealed a cystic lesion (Figures 2, 3. Red stars) with surrounding lung infiltrates (Figures 2, 3. Blue arrows). The cyst seemed to be originating from the pericardium and we suspectedan infected pericardial cyst. The patient underwent thoracotomy, which to our surprise revealed an anterior right mediastinal cyst, abutting but attached neither to the pericardium nor the lung parenchyma. Cyst was resected and histopathology revealed a mature cystic teratoma with thymic gland components present in its wall. Patient had an uneventful recovery.
Teratomas are embryonal tumors that arise from the region of the third bronchial cleft [1]. After gonads, mediastinum is the second most common location for teratomas [2]. Most of the mature teratomas in adults are asymptomatic and are often found incidentally on chest imaging. When symptoms do occur they are most commonly from these tumors compressing on nearby structures [3]. Superinfection of cystic teratomas, clinically mimicking recurrent pneumonia as in our patient, is indeed an unusual presentation. Clinicians need to be mindful of this possibility in the appropriate patient population. CT scan can provide diagnostic clues but definitive diagnosis and treatment require surgical excision.
- Raoufi M, Herrak L, Benali A, Leila Achaachi, Mustapha El Ftouh, et al. (2016) Mediastinal Mature Teratoma Revealed by Empyema. Case Reports in Pulmonology doi:10.1155/2016/7869476
- Azizkhan RG, Caty MG. Teratomas in childhood. Curr Opin Pediatr 1996;8:287–92.
- Allen MS (2002) Presentation and management of benign mediastinal teratomas. Chest Surg Clin N Am 12: 659-664.