Journal of Biostatistics & Biometrics

Article / short communication

"DNA Sequences Entropy and Long-Rang Correlated Disorder Beyond the Pair Correlations"

Sergey Melnik, Oleg Usatenko*

Department of Theoretical Physics, A. Ya. Usikov Institute for Radiophysics and Electronics Ukrainian National Academy of Science, Ukraine

*Corresponding author: Oleg Usatenko, Department of Theoretical Physics, A. Ya. Usikov Institute for Radiophysics and Electronics Ukrainian National Academy of Science, Ukraine. Tel: +7988532380; Email: olegusatenko@mail.ru

Received Date: 02 May, 2018; Accepted Date: 28 May, 2018; Published Date: 01 June, 2018




Figure 1: The conditional entropies h per symbol vs length L for R3 chromosome DNA from the Drosophila melanogaster nucleotide sequence translated into a binary file of length M  2:7´107. The low dotted line presents the entropy calculated in the framework of the method of likelihood estimation. The upper dashed line is the entropy calculated in the weak pair correlations approximation, Equation (3). The pair and third order correlation functions, solid line, are taken into account in regions r ≤ 104 and r1 < r2  ≤ 10, respectively.


Citation: Melnik SS, Usatenko OV (2018) DNA Sequences Entropy and Long-Rang Correlated Disorder Beyond the Pair Correlations. J Biostat Biom: JBSB 104.  DOI: 10.29011/JBSB-104.000004

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