1Department of Urology, Yashoda Hospital, Somajiguda, Hyderabad, India
2Department of Nephrology, Yashoda hospital, Somajiguda, Hyderabad, India
*Corresponding author: Seshu Mohan Khetavath, Department of Urology, Yashoda Hospital, Somajiguda, Hyderabad, India
Received Date: 20 December, 2020; Accepted Date: 05 February, 2021; Published Date: 08 February, 2021
Isolated tuberculous prostatic abscess is very unusual phenomenon especially in immunocompetent patient. We report an unusual presentation of tuberculous prostatic abscess in young, healthy, immunocompetent patient wherein the patient developed renal compromise due to tuberculous prostatic abscess.
Isolated tuberculous prostatic abscess is very unsual phenomenon especially in immunocompetent patient . We report an unusual presentation of tuberculous prostatic abscess in young, healthy, immunocompetent patient.
A 43 year old non diabetic, non-hypertensive male patient presented with history of on and off low grade fever, frequency, dysuria, poor stream, sense of incomplete emptying and pyuria of 7 month duration. Urine-analysis revealed plenty of white blood cells, 15-20 red blood cells, and serum creatinine of 3.9mg/dl. Ultrasound abdomen revealed bilateral grade II renal parenchymal changes with increased postvoid residual volume of 290ml (prevoid volume of 330ml). Patient denied any history of tuberculosis treatment or contact. Urethral catheterization was not successful and patient denied suprapubic catheter placement. Urine culture was negative and on Retrograde urethrogram there was posterior urethral diverticulum noted (Figure 1).
On Cystourethroscopy his anterior urethra was unhealthy, pale and membranous urethra was erythematous and congested (Figure 2A). There was a white fluffy abscess cavity involving whole of right lobe of prostate and extending up to left lobe and bladder neck with undermined edges, and there was elevated bladder neck. Verumontanum was prominent and standing out because of sloughed off prostatic cavity (Figure 2B,C) . Biopsy specimens taken from prostatic abscess cavity (Figure 2D) and bladder and sent separately for histopathology, fungal stain and TB-PCR (tuberculous polymerase chain reaction test). Cystoscopy guided Foley catheterization was done. Urine for acid fast bacilli and malignant cytology were negative. Fungal stain and bacterial culture were negative but abscess cavity tissue for TB-PCR was positive. On histopathological examination there was necrotizing chronic granulomatous inflammation. Diagnosis of tuberculous prostatic abscess with spontaneous rupture into urethra was made and patient started on Anti -Tubercular Treatment (ATT). Per urethral catheter removed after 3 weeks. Patient completed 6 months of ATT and with a serum creatinine value of 1.6mg/dl at 6months of follow up.
Tuberculous infection of the prostate can result from hematogenous seeding of the prostate at the time of initial primary tuberculous infection, or from urinary seeding after renal involvement or after intravesical bacillus Calmette- Guérin treatment for bladder carcinoma and commonly seen in immunocompromised patients [2,3]. Prostate tuberculosis involvement is usually asymptomatic and occur as an incidental histopathological finding after prostate surgery. Prostatic tuberculous cavities or abscesses may discharge into the surrounding tissues, or into urethra or forming sinuses or fistulae to the perineum or rectum .
Isolated tuberculous prostatic abscess with rupture into urethra and presenting as voiding LUTS and renal compromise in immunocompetent patient is a rare phenomenon and always differential diagnosis of genitourinary tuberculosis should be kept in mind when LUTS not responding to initial treatment.
Citation: Vaddi SP, Babu DM, Khetavath SM, Reddy RKRV, Prasad DM (2021) An Unusual Presentation of Prostatic Tuberculous Abscess - Obstructive Lower Urinary Tract Symptoms (LUTS) with Renal Compromise in an Immunocompetent Patient. J Urol Ren Dis 06: 1207. DOI: 10.29011/2575-7903.001207