Objectives: To explore the effect of adjustable sodium dialysis mode on blood pressure and blood pressure variation rate in MHD
Methods: 130 patients were included，In the experimental group(n=65) were treated with adjustable sodium dialysis.
The dialysate sodium concentration decreased gradually from 141mmol/L at the beginning of dialysis to 135mmol/L 30min before dialysis,
and 30min maintained sodium concentration 140mmol/L before the end of dialysis.The control group (n=65) were dialyzed with
constant sodium 140mmol/L. Age, sex, height, weight after last dialysis, pre-dialysis weight, dry weight and interdialysis weight
growth were measured at baseline and 1 month later, and the interdialysis weight growth rate, systolic blood pressure variation
rate and diastolic blood pressure variation rate were calculated. The differences of related indexes between the two groups were
compared between the baseline and after 1 month.
Results: After dialysis with adjustable sodium for one month, the coefficient of variation of systolic blood pressure
in the experimental group was 7.06%±3.18%, which was significantly lower than that in the control group (8.97%±5.06%, P=0.011).
Conclusion: After one month of adjustable sodium dialysis, the coefficient of variation of systolic blood pressure in MHD patients
can be reduced.
Adjustable sodium; Blood pressure; Coefficient of variation; Maintenance hemodialysis
ESRD: End-Stage Renal Disease; BPV: Blood Pressure Variability; CKD: Chronic Kidney Disease; CVD: Cardiovascular Disease;
DBP: Diastolic Blood Pressure; MAP: Mean Arterial Pressure; SBP: Systolic Blood Pressure