Journal of Pharmaceutical and Pharmacological Sciences (ISSN: 2574-7711)

Article / review article

"Survey on Awareness, Perception, and Extent of Usage of Nutraceuticals in Local Region of Uttar Pradesh, India"

*Nitesh S Chauhan, Sanjar Alam, Ashu Mittal, Jagannath Sahoo

KIET School of Pharmacy, Ghaziabad, India

*Corresponding author: Nitesh S. Chauhan, Department of Pharmaceutics, KIET School of Pharmacy, Ghaziabad UP India; Tel: +91-09999536317: Email: nitish.chauhan@kiet.edu 

Received Date: 13 April, 2017; Accepted Date 14 April, 2017: Published Date: April 21, 2017

In recent years there has been growing interest in nutraceuticals which provides health benefits and is providing preventive options for the ageing population worldwide for keeping them away from various lifestyle diseases. Along with the growing healthcare industry in India there is an emerging trend in growing consumerism for ‘Fast Moving Healthcare Goods (FMHG)’; worldwide known as Nutraceuticals, which are by definition, ingredients with human health benefits beyond basic nutrition. Global nutraceuticals market is estimated at USD149.5 Billion in 2015 growing at 7.3% (CAGR). The US has been the major market for nutraceuticals with India and China becoming fastest growing markets. According to available estimates, the global nutraceuticals product market reached $142.1 billion in 2011 and is expected to reach $204.8 billion by 2017, growing at a CAGR of 6.3%, according to a new market report from Transparency Market Research, Albany, NY. Vitamins, Minerals and Nutrients constitute about 85% of the global market while antioxidants and anti-agents account for 10% other segments such as herbal extracts occupy 5% of the market. To actualize the growth rate and the demand of nutraceuticals in the local region of Uttar Pradesh like Ghaziabad, Noida and Greater Noida, the present survey study has been conducted and the survey data was presented in a pictorial & graphical manner for better understanding.

Keywords: Nutraceuticals, FMHG, CAGR, Nutrients.

Introduction

In recent years, there is a growing interest in nutraceuticals which provide health benefits and are providing preventive options for the aging population worldwide for keeping them away from various lifestyle diseases.

Nutraceuticals are found in a mosaic of products emerging from:

  • The Food Industry
  • Herbal and Dietary Supplement Market
  • Pharmaceutical Industry, And
  • The Newly Merged Pharmaceutical/Agribusiness/Nutrition Conglomerates

Nutrients, herbals and dietary supplements are major constituents of nutraceuticals which make them instrumental in maintaining health, act against various disease conditions and thus promote the quality of life

Broadly Can be Classified As

  1. Nutrients: These are the substance which has established nutritional functions. Eg: Vitamins, Minerals, Amino acids, Fatty acids etc.
  2. Herbals/ phytochemicals: Herbs or Botanical products.
  3. Dietary supplements: probiotics, prebiotics, antioxidants, enzymes etc.

Consumers are increasingly becoming health conscious and realizing the importance of dietary supplement to help them deal with fast changing lifestyle, which has put them at risk of diabetes , cholesterol, heart problems. Nutraceutical products play a vital role in such a scenario.

Market Segmentation

Indian nutraceutical market is composed of food supplements, vitamins and mineral supplements. Food supplement includes protein powder, pediatric nutrition and clinical products.

 

The nutraceutical market in India is estimated to be at least INR 44 billion with functional food forming largest category with 54%.

Functional Food

 The major share is held by food products and supplements, valued at INR 5.63 billion in 2007. The next major pie is held by malted beverages (Horlicks, Complan, Boost and Red Bull), valued at INR 3.38 billion.

Nutrients

Most common nutrients used/ supplemented as nutraceuticals are minerals and vitamins or in combination with other antioxidants.

Health Benefits of Different Common Nutrients

Vitamins

 Fat soluble vitamins

Vitamin A: Act as antioxidants, essential for growth and development, maintains healthy vision, skin and mucous membranes, may aid in the prevention and treatment of certain cancers and in the treatment of certain skin disorders.

  • Vitamin D: Essential for formation of bones and teeth, helps the body to absorb and use calcium.
  • Vitamin E: Antioxidants, helps to form blood cells, boost immune system.
  • Vitamin K: Essential for blood clotting.

Water soluble vitamins

  • Vitamin C: Antioxidants, necessary for healthy bones, gums, teeth and skin.

Helps in wound healing, prevent from common cold.

  • Vitamin B1: Helps in carbohydrate metabolism, essential for neurological function.
  • Vitamin B2: Energy metabolism, maintains healthy eye, skin and nerve function.
  • Vitamin B3: Energy metabolism, brain function.
  • Vitamin B6: Helps to produce essential proteins to energy.
  • Vitamin B12: Help in producing genetic material formation of RBC, maintenance of CNS, synthesis of amino acids, involved in metabolism of proteins, fats and carbohydrates.

Folic Acid: Helps in RBC formation, formation of genetic material of cell, very much essential during pregnancy.

Pantothenic Acid: Aids in the synthesis of cholesterol, steroids and fatty acids, crucial for intra-neuronal synthesis of acetylcholine.

Vitamins like Compounds

  • L-Carnitine: Helps in oxidation of fatty acids, role in oxidative phosphorylation.
  • Choline: Lipotropic agents, used to treat fatty liver and disturbed fat metabolism.
  • Inositol: For amino acid transport and movement of potassium and sodium.
  • Taurine: Helps in retinal photoreceptor activity, bile acid conjugation, WBC antioxidant activity, CNS neuro-modulation, platelet aggregation, cardiac contractibility, sperm motility, insulin activity.

Minerals

  • Calcium: Essential for bone and teeth, maintaining bone strength, nerve muscle and glandular function, blood clotting.
  • Iron: Energy production, Hemoglobin, oxygen transport.
  • Magnesium: For healthy nerve and muscle function, bone formation.
  • Phosphorus: Energy production, phosphorylation process, bone and teeth, for genetic material.
  • Cobalt: Components of vitamin B12 coenzyme.
  • Copper: Hemoglobin and collagen production, function of heart, energy production, absorption of Iron.
  • Iodine: Proper function of Thyroid gland.
  • Chromium: With insulin it helps in conversion of Carbohydrate and Fat into energy , treatment of Diabetes.
  • Selenium: Antioxidant, functioning of heart muscle, parts of GPx enzyme.
  • Zinc: Essential for cell reproduction for development in neonates, wound healing, production of sperm and testosterone hormone.

 Herbals

  • Aloe Vera: Anti inflammatory, emollient, wound healing.
  • Primrose oil: Dietary supplement of linolic acid, treatment of ectopic eczema.
  • Garlic: Antibacterial, antifungal, antithrombotic, anti inflammatory.
  • Ginger: Carminative, antiemetic, treatment of dizziness.
  • Ginseng: Adaptogen.
  • Green tea: Antioxidant reduces risk of CVDs, enhance humoral and cell mediated immunity.

Vegetables, fruits, whole grain, herbs, nuts and various seeds contains an abundance of phenolic compounds, terpenoids, sulphur compounds, pigments etc that has been associated with protection /treatment of certain disease conditions.

Phytochemicals

Health Benefits

  • Substrate for Biochemical Reaction.
  • Cofactor for Enzymatic Reactions
  • Inhibitors of Enzymatic Reactions.
  • Absorbents That Binds To And Eliminate Undesirable Constituents In The Intestine.
  • Scavengers of Reactive or Toxic Chemicals.
  • Enhance The Absorption And/ Or Stability Of Essential Nutrients.
  • Selective Growth Factors for Beneficial Bacteria.
  • Selective Growth Factors for Beneficial Bacteria.
  • Fermentation Substrate for Beneficial Bacteria.

Nutraceutical Market Overview

Global Market Overview

Nutraceuticals and functional food ingredients are by definition, ingredients in pharmacological activity for human health benefits beyond basic nutrition as they are sold as isolated, purified components in pharmacological doses for specific ailments. Health is one of vital importance to consumer of all ages, demographic groups and countries, so one would expect a strong demand for nutraceutical foods & beverages which provide specific health benefits.

The international market for nutraceuticals is expanding and new research is constantly being conducted.

Nutraceuticals is an evolving concept with varying definitions across countries:

Definition of nutraceuticals as per various legislation around the globe

  • USA
  • Known as- Dietary Supplements
  • Governed By- Food & Drug Authority
  • Implemented in- 1994

Definition Covers- Vitamins, Minerals, Herbs, Amino Acids, Metabolite

  • India
  • Regulation- Food Safety & Standard Act (FSSA)
  • Effective from- Passed in 2006.
  • Definition Covers-Plant or Botanicals, Minerals, Vitamins, Amino Acids & Enzymes, Substances from Animal origin, Dietary Supplements.

Globally, this market is expected to reach USD 180 billion in 2013 growing at a CAGR of 70% driven by the fastest growing dietary supplement category.

Indian Market Overview

  • Nutraceuticals is an evolving segment in India, more & more Pharmaceuticals, FMHG; FMCG companies are entering in to this segment.
  • Companies are focusing on this segment as preventive therapy rather than curative therapy.
  • Consumers are increasingly becoming health conscious and realizing the importance of dietary supplements to help them deal with fast changing life styles.
  • The Nutraceuticals Market in India is estimated to be INR 44 Billion with functional food forming largest category with 54% share.

There are many factor which are governing the growth of Neutraceuticals

Affluence: Increased affluence of ever growing working population with changing life styles is leading to change dietary habits.

Increase of working population by 30 million from 2005-2015 + increasing income level of the Indian population

Affordability: Reduced affordability of sickness related expenditure is driving consumers towards wellness.

Out of pocket expenditure constitutes 64% of health care expenditure in India as compared to 18% globally.

  • While increased physician awareness is driving prescriptions of nutrition supplements, penetration growth of media & diagnostic centers is helping to create awareness

Physician awareness about health benefits of nutraceuticals has fuelled growth in nutrition related prescription at 26% CAGR in recent years.

High media penetration is improving Consumers awareness

With growing diagnostic centers the awareness about health disorders and deficiencies is increasing.

  • : Emergence of newer distribution channels is fueling accessibility to Nutraceuticals

Emergence of wellness products and services related retail outlets is also driving accessibility of nutraceuticals

Growing organized retail has emerged as a new channel for distribution of nutraceuticals.

Many new players

  • Alkem Laboratories: Alkem Laboratories has invested over INR 1 billion to create exclusive manufacturing facilities for their health food business.

Alkem Health Foods is expected to generate a turnover of over INR 3-5 billion

Annually, in a few years.

  • Plethico: The Company recently acquired a USD 100 million nutraceutical companies named Natrol Inc. in the US and is planning to launch its 700 odd products in India and other global market.
  • Divi’s Laboratories: Divi’s Laboratories has set up a INR 350 million nutraceutical plant and has a separate arm, Divi’s Nutraceuticals.
  • Mission Vivacare: Mission Vivacare is investing over INR 800 million in modern manufacturing facilities to launch its products globally under the brand name- Mission Vivaprime

Regulations

  • The food sector in India is governed by a multiplicity of laws under different ministries , a number of committees , including the standing committee of Parliament on Agriculture in its 12th report submitted in April 2005, have emphasized the need for a single regulatory body and food integrated food law.
  • The Indian Food Safety and Standards Bill 2005 have been signed into law, promising a major impact on the Indian food processing industry.
  • The Food Safety and Standard Act aims to integrate the food safety laws in the country in order to systematically and scientifically develop the food processing industry and paradigm shift from a regulatory regime to self compliance.

The main objectives of the Act are:

  1. To introduce a single statute relating to food , and
  2. To provide for scientific development of the food safety processing industry.

Highlights of the Act:

  • The Food Safety and Standards Act consolidate eight laws governing the food sector and establish the Food Safety and Standards Authority (FSSA) to regulate the sector and other allied committees.
  • The FSSA would consist of a Chairperson and 22 members. The Chairperson would be either an eminent food scientist or a civil servant not below the rank of secretary. Seven of the members would be ex-officio, not below the post of Joint Secretary from various ministries. Five members would be appointed by rotation every three years from the states and Union Territories. The authority would have two representatives each from the food industry and consumer organizations, three food technologists, and two members from a former organization and one from retail organization.
  • Everyone in the food sector is required to get a license or a legislation that would be issued by local authorities.
  • The law will be enforced through state commissioners of food safety and local level officials. The Act empowers the FSSA and state food safety authorities to monitor and regulate the food business operators.
  • The Act provides for a graded penalty structure where the punishment depends on the severity of the violations.
  • New Judicial Process : in order to judge cases related to breach of specified regulations , the state government has the power to appoint an adjudicating officer , not below the rank of Additional District Magistrate , any person not satisfied by the decision an Adjudicating officer has the right to appeal to the Food Safety Appellate Tribunal.
  • Food Recall Procedures: every distributor is required to identify any food article to its manufacturer and every seller to its distributor. Anyone in the sector should be able to initiate recall procedures if he finds that the food sold has violated specified standards.

Research Methodology

Product Selected:

Questionnaire

Results

The Project Report requires the actualization of Nutraceuticals Market in the area of Ghaziabad, Noida & Greater Noida. To fulfill required parameter, a survey Questionnaire was designed & implemented in following grounds-

  • Market Share of Nutraceuticals.
  • Retail Business.
  • Growth Rate of Nutraceuticals.
  • Status of Generic manufacturer in Nutraceuticals.
  • Individual Product Sale.

The present finding can be envisaged as the future prospective to hold the new vast state art to fit the growth of Nutraceuticals. To actualize the growth rate & the demand of Nutraceuticals in present scenario, Various survey studies have been conducted. Data was portrait & presented in pictorial & Graphical Manner for better understanding.

Conclusion

  • Nutrition is fundamental need, various risk factors related to health results from imbalance nutrition.
  • India is developing country with average food supplements, which reach to the countryman. Therefore, it is important everyone to consider & include Nutraceuticals in our proper balance diet.
  • Data indicates that HAJMOLA has got the highest unit sale of 43560 Sachets followed by GLUCON-D (HEINZ) 40460 & then ELECTROL (FDC) of 29280.
  • SUGARFREE & REVITAL Annual unit sale is more than 12000 units.
  • The Total Growth in sales from 2009-10 to 2010-11 is 26%.
  • Data indicates that there is a high demand of Branded product rather than the Generic one, & ultimately it’s the health issue.
  • Conclusion can be drawn & can be said that it is the Brand Era of Nutraceuticals.

Figure 1: Global Nutraceutical Market

Indian Nutraceutical market in 2008 in USD 1 billion

 

Figure 2: Indian Nutraceutical Market

Globally, this market is expected to reach USD 180 billion in 2013 growing at a CAGR of 70% driven by the fastest growing dietary supplement category.

Figure 3: Global Nutraceutical Market and Expected Growth

Figure 4: Growth in market in India is driven by several factors

There are many factor which are governing the growth of Neutraceuticals

 

Figure 5: Average cost of inpatient treatment both in rural and urban India has doubled in last decade.

 

 

Figure 6: Awareness of Nutraceutical

 

Figure 7: Accessibility

 

.

 

Figure 8: Comparative Data of Annual Average Sales (2009-10 Vs.2010-11)

Figure 9: Over All Growth In Annual Average Sales (2009-10 vs. 2010-11)

 

Figure 10: Product Annual Unit Sale

 

Figure 11: Status of Generic Manufacturer to Penetrate this Market

 

 

 

 

 

 

 

 

 

 

Class/Component

 

 

Source

 

 

Potential Benefits

 

1.Fatty Acids

Milk ,Meat

Improve Body Compositions,

a. CLA

Fish oil, birseen and maize

Reduce Cancers

b. n-FA (DHA,EPA)

fodder, mustard, linseed, rapeseed

Reduce CVD and improve, mental and visual function

2.Polyphenols

Fruits

Neutralize free radicals, reduce

a. Anthocyanidin

Tea, babul pods, Mustard

risk of cancers

b. Catechins

cake, rape seed, salseed

Neutralize free radicals, reduce

c. Flavonone

Citrus

risk of cancers

d. Flavones

 

Neutralize free radicals, reduce

3.Proanthocyanidine

Fruits, vegetables, soya bean

risk of cancers

a. Saponins

Cocoa, chocolate, tea, rape seed

Neutralize free radicals, reduce

b. Probiotics/Prebiotics/Synbiotics

Soyabeans, chick pea

Reduce CVD

c. Lactobacillus

 

 

d. Fructo-oligo sacchrides

 

 

4.Phytoestrogen

Curd, yoghurt

Lower cholesterol, anticancer

a. Daidzein

Whole grains, onions

Improve G.I health

b. Zenistein

combination of pro & Prebiotics

Improve G.I health

c. Lignans

 

 

5.Carotinoids

Soyabean, falax, lentiseed

Reduce menopause symptoms, increases bone health

a. B-Caroteine

 

 

b. Tuteine

Flax, rye, vegetables

Reduce cancer and heart disease

c. Zeoxanteine

 

 

d. Lycopene

 

 

6.Dietary Fibers

Birseen & maize fodder,

Neutralize free radicals

a. Insoluble fiber

carrots, vegetables, fruits

Vegetables

Healthy vision

b. b-glucagon

Eggs, citrus, corn

Healthy vision

c. whole grain

Tomatoes

Reduce prostate cancer

 

Wheat bran, Oats, Cereal grains

Reduce breast cancer, colon, cancer, Reduce CVDs

Table1: Examples of functional components

 

 

Indian Pharmaceutical Market

(43.9)

 

Functional Food (23.9)

Nutrition Fortified Food

Probiotics

Functional Beverages (6.0)

Sports & Energy Drinks

Fortified Juices

Glucose Powder

Dietary Supplements(14.0)

Vitamins Supplements

Mineral supplements

Macronutrients

Antioxidants

Tonic

Extracts

Table 2: Depiction of Indian Nutraceutical Market

 

 

Phytochemicals

 

 

Source

 

 

Role

 

Tocotrienols & tocopherols

 

Grains

 

 

Suppressed the growth of diverse tumors cell lines via inhibition of apoptosis and concomitant arrest of cells in the G1 phase of cell division.

Carotenoids

 

 

Fruits and vegetables

 

 

Antioxidants, protects against uterine, prostate colorectal, lung & digestive tract cancer and protection to other antioxidants.

Limonoids

 

Citrus fruits

 

Inhibiting phase 1, enzymes and inducing phase2 detoxification enzymes in liver, provide protection to lung disease.

 

Glucosinolates

 

 

 

Cruciferous

 

 

Activation of liver, detoxification enzymes inhibits the neoplastic effects of various carcinogens.

Fiber

Vegetables & fruits

Protect against colorectal disease.

Table 3: Various Phytochemicals their Source and Roles

 

 

S. No

 

 

Type of Product

 

 

Leading Brand

 

 

Company

 

 

Market Size

 

 

Food Product

Sugar free

Zydus Wellness

INR 5.63 billion

1

 

Malted beverages

Fruit based

Dekrice

Horlicks

Wockhardt

GSK

INR 3.38 billion

INR 0.68 billion

2

products

Complain

Heinz

INR 0.56 billion

 

Pediatric nutrition

Bourn vita

Cadbury

INR 0.56 billion

3

 

 

Protein powder

 

Red bull

GSK

Red bull

INR 0.23 billion

INR 0.23 billion

4

Sports product

Real

Dabur

 

 

Clinical product

Tropicana

Pepsi food

 

 

 

 

Lactigen

Nestle

Lactodex

Dexaloc

Raptakos

Wockhardt

Pediasure

Abott

Protenex

Wockhardt

GRD

zydus

Glucon D

glucose D

british biological

Heinz

ORS

Dabur

Revital

Ranbaxy

Electoral

FDC

Table 4: Indian food supplement segmentation

 

                Hepatoglobine Syrup        •      Zevit Capsules

                   Lactodex 500 gm                •      Complan 500 gm

                   Nutrimom 200 gm            •   Glucon D 100 gm

             Threptin Diskettes 275 gm       •      Revital Capsules

                      Zerolac 400 gm             •      Reconia Tablets

                Sugar Free 300+30 pallet           •      GRD Biscuit 250 gm

                        Protinex 200 gm                •      Shelcal 500 Tablets

                        Horlicks 500 gm                 •      Chyawanprash 1 kg

                          Boost 500 gm       •      Hajmola 1*6

                    Cobadex Forte capsule           •      Dabur Honey 50 gm

                           Fefol Capsules               •      Pedia Sure 400 gm

                    Ostocalcium B12 syrup       •      PediaLyte 500 ml

                    Lactogen No. 1 475 gm      •      Electral 21.8 gm

                         Everyday 500 gm        •      Enerzal 50 gm

Product Selected

 

 

 

 

Citation: Chauhan NS, Alam S, Mittal A, Sahoo J (2017) Survey on Awareness, Perception, and Extent of Usage of Nutraceuticals in Local Region of Uttar Pradesh, India. J Pharma Pharma Sci, 2017: JPPS-129

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